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目的 :研究单磷酸阿糖腺苷联合苦参素注射液治疗慢性乙型肝炎的临床疗效。方法 :选择 15 9例慢性乙型肝炎患者 ,随机应用单磷酸阿糖腺苷联合苦参素注射液治疗与应用甘利欣治疗作为对照 ,评估两组对肝功能 ,肝纤维化指标和HBV复制的疗效。结果 :治疗组在改善肝功能、肝纤维化指标及在HBsAg、HBeAg、HBV -DNA阴转率方面均显著优于对照组 ( P <0 .0 1)。结论 :单磷酸阿糖腺苷联合苦参素治疗慢性乙型肝炎有肯定的效果。
Objective: To investigate the clinical efficacy of valacetin monophosphate combined with oxymatrine injection in the treatment of chronic hepatitis B patients. Methods: Fifty-nine patients with chronic hepatitis B were randomly divided into two groups: randomized treatment with Glyphosate monophosphate combined with oxymatrine injection and glycyrrhizin treatment as control group, and the effects of liver function, liver fibrosis markers and HBV replication Efficacy. Results: The treatment group was significantly better than the control group (P <0.01) in improving liver function, indicators of liver fibrosis and in the negative conversion rate of HBsAg, HBeAg and HBV-DNA. CONCLUSION: Araindosine monophosphate combined with oxymatrine has a positive effect in the treatment of chronic hepatitis B.