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目的探讨地诺前列酮栓联合人工破膜和静滴缩宫素对产程的影响。方法选择2010年2月1日-2012年2月1日在我院行地诺前列酮栓引产,未成功临产需终止妊娠的初孕妇240例,随机分成2组,每组120例。A组地诺前列酮栓取出后行人工破膜加静滴缩宫素引产,B组取出地诺药列酮栓后等待自然临产,比较两组孕妇的阴道试产成功率、剖宫产率、24 h产后出血率及新生儿窒息情况。结果试产成功率A组为79.17%,B组为54.17%;剖宫产率A组为20.83%,B组为45.83%;早期产后出血率A组为0.83%,B组为5.83%;羊水Ⅲ度污染率A组为2.5%,B组为8.33%。两组比较差异均有统计学意义。结论地诺前列酮栓促宫颈成熟协同人工破膜加静滴缩宫素可明显降低剖宫产率,降低羊水污染率及早期产后出血率,并能及时了解羊水情况,确保母婴安全。
Objective To investigate the effects of dinoprostone suppository combined with artificial rupture of membranes and intravenous oxytocin on labor process. Methods Select February 240, 2010 - February 1, 2012 in our hospital norethisterone suppository, the first trimester pregnant women who failed to abortion on termination of labor 240 cases were randomly divided into two groups of 120 cases. A group of dinoprostone suppository after removal of artificial rupture of the membrane plus intravenous oxytocin induced abortion, B group to take norelsetin suppository waiting for natural abortion, compared the success rate of vaginal trial production of two groups of pregnant women, cesarean section rate , 24 h postpartum hemorrhage rate and neonatal asphyxia. Results The success rate of trial production was 79.17% in group A, 54.17% in group B, 20.83% in group A and 45.83% in group B. The rate of early postpartum hemorrhage was 0.83% in group A and 5.83% in group B, Grade III contamination was 2.5% in group A and 8.33% in group B. The difference between the two groups was statistically significant. Conclusions Dinoprostone suppository cervical ripening combined with artificial rupture of membrane plus intravenous oxytocin can significantly reduce the rate of cesarean section, reduce amniotic fluid contamination rate and early postpartum hemorrhage rate, and can understand the amniotic fluid situation in time to ensure the safety of mother and baby.