论文部分内容阅读
目的:探讨二级前哨淋巴结活检技术应用于进展期胃癌手术的可行性。方法:对2010年1月—2012年6月应用二级前哨淋巴结技术行胃癌根治术68例患者和同期常规行胃癌D2根治术76例患者的手术时间、术中出血量、清除淋巴结数目、术后并发症、住院天数等方面进行对比分析。结果:144例手术均获成功,与常规行D2根治术比较,应用二级前哨淋巴结技术组手术时间延长[(203.7±40.4)min vs.(150.5±32.1)min],但清除淋巴结数目增多[(18.5±0.6)vs.(14.5±0.5)],术后2年生存率增加[84.7%vs.74.2%],差异均有统计学意义(均P<0.05);两组在出血量[(143.2±10.5)m L vs.(131.6±23.5)m L]、住院天数[(11.5±0.4)d vs.(10.6±0.3)d]等方面差异均无统计学意义(均P>0.05)。结论:与常规胃癌根治术相比,应用二级前哨淋巴结活检技术在不增加术中出血量及住院天数的前提下,能提高患者术后2年生存率。
Objective: To investigate the feasibility of secondary sentinel lymph node biopsy in the treatment of advanced gastric cancer. Methods: From January 2010 to June 2012, 68 patients undergoing radical gastrectomy with gastric cancer undergoing second grade SLN and 76 patients undergoing D2 radical gastrectomy during the same period were selected for operation time, blood loss, number of lymph nodes removed, Postoperative complications, hospital days and so on comparative analysis. Results: All the 144 surgeries were successful. Compared with conventional D2 radical mastectomy, the operative time of secondary SLNT was longer ([203.7 ± 40.4] min vs. (150.5 ± 32.1) min], but the number of clear lymph nodes increased (18.5 ± 0.6) vs. (14.5 ± 0.5)], and the 2-year survival rate increased 84.7% vs 74.2% (all P <0.05) 143.2 ± 10.5) m L vs. (131.6 ± 23.5) m L], length of hospital stay [(11.5 ± 0.4) d vs. (10.6 ± 0.3) d], respectively. Conclusion: Compared with the conventional radical gastrectomy, the application of SLN2 biopsy can improve the 2-year survival rate of patients without increasing the intraoperative blood loss and hospitalization days.