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目的:总结70例妊娠及哺乳期乳腺癌的治疗和预后情况。其中Ⅰ期乳腺癌11例;Ⅱ期43例;亚期16例。结果:TNM分期、手术方式和治疗时间对病人的5年生存率有显著性意义(P<0.05),是否终止妊娠则无显著性意义(P>0.05)。本病治疗原则与一般乳腺癌相同,首选治疗方法是根治术或改良根治术,术后辅助放疗和化疗,其5年生存率分别为55.7%和74.3%,结论:终止妊娠不能提高病人生存率,目前尚无资料显示再次妊娠是否有害,Ⅰ期乳腺癌病人应在治疗2年后再考虑妊娠,Ⅱ、Ⅲ期乳腺癌病人预后较差,应避免再次妊娠或在治疗结束5年后再考虑妊娠。
Objective: To summarize the treatment and prognosis of 70 cases of pregnant and breast cancer. There were 11 cases of stage I breast cancer; 43 cases of stage II; 16 cases of sub-period. Results: The 5-year survival rate of patients with TNM staging, surgical methods, and treatment time was significant (P<0.05), and there was no significant difference in the termination of pregnancy (P>0.05). The principle of treatment of this disease is the same as that of normal breast cancer. The preferred treatment method is radical or modified radical surgery. Postoperative adjuvant radiotherapy and chemotherapy have a 5-year survival rate of 55.7% and 74.3% respectively. Conclusion: Termination of pregnancy cannot Improving patient survival rates, there is currently no data to show whether second trimester is harmful, patients with stage I breast cancer should consider pregnancy after 2 years of treatment, patients with stage II and III breast cancer have a worse prognosis, and should avoid re-pregnancy or end of treatment. 5 Years later consider pregnancy.