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目的 :观察异丙酚复合小剂量氯胺酮在人工流产中的疗效。方法 :对 10 0例自愿终止妊娠的早孕妇女 ,在常规消毒的同时 ,静脉注射异丙酚 1mg/kg加氯胺酮 0 5mg/kg。观察麻醉效果 ,宫口松弛 ,人工流产综合征发生率及出血量 ,并分别记录麻醉前后呼吸及循环参数的变化 ,以及苏醒情况。结果 :异丙酚复合小剂量氯胺酮起效快 ,镇痛效果明显 ,有效率达 98%。与对照组比较差异有显著性 (P <0 .0 1)。宫口松弛与对照组比较有差异性 (P >0 .0 5 )。诱导前、后呼吸循环参数无明显变化。无 1例发生人工流产综合征 ,与对照组比较 ,有显著差异 ,出血量与对照组比较无显著差异。结论 :异丙酚复合小剂量氯胺酮静脉麻醉是人工流产的适宜麻醉方法之一 ,可达到无痛人工流产的良好效果 ,值得推广应用。
Objective: To observe the effect of propofol combined with low-dose ketamine in induced abortion. Methods: A total of 100 pregnant women who voluntarily terminated pregnancy were injected intravenously with propofol 1 mg / kg and ketamine 0 5 mg / kg while routine disinfection. The effects of anesthesia, relaxation of cervix, the incidence of induced abortion syndrome and the amount of bleeding were observed. The changes of respiration and circulation parameters before and after anesthesia were recorded, and the status of recovery was recorded. Results: Propofol combined with low-dose ketamine has rapid onset and analgesic effect with an effective rate of 98%. Compared with the control group, the difference was significant (P <0.01). Cervical relaxation compared with the control group were different (P> 0.05). No significant changes were found in respiratory parameters before and after induction. No one case of induced abortion syndrome, compared with the control group, there were significant differences in bleeding volume compared with the control group no significant difference. Conclusions: Propofol combined with low-dose ketamine intravenous anesthesia is one of the suitable anesthetic methods for induced abortion, which can achieve the good effect of painless induced abortion and is worth popularizing and applying.