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应用 IHA 试验检查了1063例新生儿脐带血,其中正常和异常儿弓形虫抗体阳性率分别为2.54%和13.16%,差异非常显著(P<0.01)。出生后6~12月,对脐带血阳性的28名儿童进行了随访,其中3名儿童抗体仍为阳性,另有2名死亡。用 IHA 和 ELISA-IgG 方法检测了181例残弃儿和191例正常儿,总阳性率分别为33.15%和9.95%,差异亦非常显著。同时观察了76份中枢神经系统感染患儿的脑脊液,弓形虫抗体阳性9例,镜检活虫者3例,其中一例动物接种成功。提示弓形虫感染对引起出生缺陷和智能低下起重要作用。
The cord blood of 1063 newborns was examined by IHA test. The positive rates of normal and abnormal T. gondii antibodies were 2.54% and 13.16%, respectively, with significant difference (P <0.01). From December to December after birth, 28 children with cord blood were followed up. Three of the children were still positive and two others died. The total positive rate of 181 cases and 191 normal children detected by IHA and ELISA-IgG method were 33.15% and 9.95%, respectively. The difference was also significant. Cerebrospinal fluid was also observed in 76 children with CNS infection. Toxoplasma gondii antibody was positive in 9 cases and microscopic examination in 3 cases. One case of animal was inoculated successfully. Toxoplasma gondii infection prompted to cause birth defects and mental retardation plays an important role.