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本文报告以组胺释放率、血清总 IgE、尘螨特异性 IgE 及皮肤挑刺试验等为指标,进一步探究温阳片预防支气管哮喘发作的机理。在温阳片获效的同时,哮喘患者血清总 IgE 和尘螨特异性 IgE 的季节性升高受到明显抑制,组胺释放率明显下降;尘螨皮肤挑刺试验也呈好转趋势,表明温阳片可能通过抑制总 IgE 和特异性 IgE 的季节性升高,从而减少组胺等过敏介质的释放,以至减轻或中止哮喘的季节性发作。本文报告以组胺释放率、血清总 IgE、尘螨特异性 IgE 及皮肤挑刺试验等为指标,进一步探究温阳片预防支气管哮喘发作的机理。在温阳片获效的同时,哮喘患者血清总 IgE 和尘螨特异性 IgE 的季节性升高受到明显抑制,组胺释放率明显下降;尘螨皮肤挑刺试验也呈好转趋势,表明温阳片可能通过抑制总 IgE 和特异性 IgE 的季节性升高,从而减少组胺等过敏介质的释放,以至减轻或中止哮喘的季节性发作。
In this paper, histamine release rate, serum total IgE, dust mite specific IgE and skin prick test as an index to further explore the Wen yang tablets prevent bronchial asthma attack mechanism. In the meanwhile, the seasonal increase of total serum IgE and dust mite-specific IgE in asthma patients was significantly inhibited and the histamine release rate was significantly decreased. The pick-up test on dust mite skin also showed a tendency of improvement, It is possible to reduce or stop the seasonal attack of asthma by inhibiting the seasonal increase of total IgE and specific IgE, thereby reducing the release of allergic mediators such as histamine. In this paper, histamine release rate, serum total IgE, dust mite specific IgE and skin prick test as an index to further explore the Wen yang tablets prevent bronchial asthma attack mechanism. In the meanwhile, the seasonal increase of total serum IgE and dust mite-specific IgE in asthma patients was significantly inhibited and the histamine release rate was significantly decreased. The pick-up test on dust mite skin also showed a tendency of improvement, It is possible to reduce or stop the seasonal attack of asthma by inhibiting the seasonal increase of total IgE and specific IgE, thereby reducing the release of allergic mediators such as histamine.