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对２０６例静脉毒瘾者和２１１例性乱女子进行了ＨＧＶ感染状况的研究。 ＨＧＶ ＰＣＲ选择扩增位于５’非结构区基因组（ＮＳ５区），扩增产物为１９０ｂｐ。结果：２０６例静脉毒瘾者ＨＧＶ感染率为１８．４％（３８／２０６），其抗ＨＧＶ－ＩｇＧ和ＨＧＶ、ＲＮＡ的检出率分别为１２．１％（２５／２０６）、 ９．２％（１９／２０６），两者同时阳性的检出率为２．９％（６／２０６）；２１１例性乱者 ＨＧＶ感染率 ６．６％（１４／２１１），其抗 ＨＧＶ－ＩｇＧ和 ＨＧＶ－ＲＮＡ的检出率分别为 １．４％（３／２１１）、５．２％（１１／２１１），没有检测到两者同时阳性。ＨＧＶ标志阳性５２例中ＨＢＶ－ＤＮＡ均为阴性。ＨＣＶ－ＲＮＡ阳性１０例，其中 ８例为抗 ＨＧＶ－ＩｇＧ阳性， ２例为 ＨＧＶ－ＲＮＡ阳性。 ＨＣＶ－ＲＮＡ阳性者８例分布在静脉毒瘾组，性乱组仅为２例。检测５２例ＨＧＶ感染者ＡＬＴ均属正常范围。我们的研究发现静脉毒瘾者和性乱者ＨＧＶ血清标志的检出率显著高于献血员和非甲—成肝炎患者的ＨＧＶ血清标志检出率，证实了静脉毒瘾者是ＨＧＶ感染的高危人群，ＨＧＶ也可通过性接触而传播。
HGV infection was studied in 206 intravenous drug addicts and 211 cases of sexual abusers. HGV PCR selective amplification is located in the 5 ’non-structural region of the genome (NS5 region), the amplification product was 190bp. Results: The prevalence of HGV infection in 206 intravenous drug users was 18.4% (38/206). The detection rates of anti-HGV-IgG, HGV and RNA were 12.1% (25/206), 9.2 % (19/206), the positive rate of both was 2.9% (6/206); 211 cases of HGV infection rate was 6.6% (14/211), the anti-HGV-IgG and The detection rates of HGV-RNA were 1.4% (3/211) and 5.2% (11/211), respectively. No positive results were found. HBV-DNA was negative in 52 cases with positive HGV markers. 10 were positive for HCV-RNA, of which 8 were anti-HGV-IgG positive and 2 were HGV-RNA positive. 8 cases of HCV-RNA positive were distributed in intravenous drug addiction group, only 2 cases of sexual disorder group. Detection of 52 cases of HGV infection ALT are within the normal range. Our study found that the detection rate of HGV serum markers in intravenous addicts and sexual persons was significantly higher than that of HGV seroprevalence in blood donors and non-A-hepatitis patients, confirming the high risk of HGV infection in intravenous addicts People, HGV can also be transmitted through sexual contact.