论文部分内容阅读
人类和猿猴类疟疾的复发目前认为源于初次红外期裂体增殖后留存在肝细胞中的休眠子。过去由于缺乏合适的红外期培养系统,复发型疟疾红外期的研究受到了限制。最近作者等(1985年)用间日疟原虫Chessen株和ONG株子孢子接种于人肝肿瘤细胞(HepG_2—A16)体外培养红外期获得成功,并发现有两种类型的红外期疟原虫。一型是快速分裂的裂殖体,于培养9天后释放出裂殖子,另一型是不分裂并在首批裂殖体自培养中消失后仍继续存留的休眠子。
Recurrence of malaria in humans and simian species is currently thought to stem from the dormancy found in hepatocytes after the initial inflorescence division. In the past, due to the lack of a suitable infrared culture system, the research on IR of recurrent malaria has been limited. Recently, et al. (1985) succeeded in culturing human hepatoma cells (HepG_2-A16) with Cesium vivax and ONG strain sporozoites in vitro, and found two types of Plasmodium falciparum. One type is a rapidly dividing schizont and releases merozoites 9 days after culture and the other type is a dormant child that does not divide and persists after the first batch of schizonts has disappeared from the culture.