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目的探讨胞二磷胆碱和抚触对新生儿缺氧缺血性脑病(HIE)患儿的效果。方法将252名HIE患儿按随机分治疗组(胞二磷胆碱和抚触组)132名和对照组(胞二磷胆碱组)120名,通过对患儿治疗前后的NBNA评分、智力发育指数(MDI)、运动发育指数(PDI)及体重、身高、头围等进行评估。结果治疗组较对照组的NBNA评分、MDI、PDI和体格发育明显提高,差异有统计学意义。结论胞二磷胆碱和抚触对新生儿缺氧缺血性脑病患儿生长发育有一定的临床疗效。
Objective To investigate the effect of citicoline and touch on neonates with hypoxic-ischemic encephalopathy (HIE). Methods A total of 252 children with HIE were randomly divided into treatment group (citicoline and stroking group) 132 and control group (citicoline group) 120. Through the NBNA score of children before and after treatment, mental development Index (MDI), sports development index (PDI) and weight, height, head circumference, etc. were evaluated. Results The NBNA score, MDI, PDI and physical development of the treatment group were significantly higher than those of the control group, the difference was statistically significant. Conclusion Citicoline and touch have some clinical effects on the growth and development of neonates with hypoxic-ischemic encephalopathy.