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金莲花为清热解毒中药,具明显的抗炎活性,主治上呼吸道感染、扁桃体炎、咽炎等症。其化学成分主要含黄酮类、酚酸类和生物碱类,但有效成分不确定。采用RAW264.7细胞构建的体外炎症模型研究了金莲花总提取物、总黄酮和总酚酸的抗炎活性。结果表明,金莲花的总黄酮和总酚酸都有明显的抗炎活性,总黄酮略优于总酚酸,但二者的活性都优于总提取物。
Nasturtium detoxification traditional Chinese medicine, with significant anti-inflammatory activity, attending upper respiratory tract infection, tonsillitis, pharyngitis embolism. Its chemical composition mainly contains flavonoids, phenolic acids and alkaloids, but the active ingredient is uncertain. In vitro inflammatory model of RAW264.7 cells was used to study the anti-inflammatory activity of the total extract, total flavonoids and total phenolic acids. The results showed that the total flavonoids and total phenolic acids have significant anti-inflammatory activity, total flavonoids slightly better than the total phenolic acid, but the activity of both are better than the total extract.