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目的:了解新疆哈萨克族9～10岁儿童动态血压昼夜节律,测定其生化指标并与全国儿童的各参数水平相比。方法:选择新疆巴里坤地区9～10岁健康儿童49名,男27名,女22名;年龄(9.7±0.5)岁,身高(139.67±7.51)cm,体质量(30.91±6.15)kg,体质量指数(15.73±2.00)kg/m2。采用无创性携带式动态血压监测仪对受试者的动态血压进行监测,受试者集中居住48h,饮食自理,习惯照旧,正确收集24h尿量,询问病史和体检。抽空腹血分离血清,保存于-40℃深低温下待测。并将49名受试儿童动态血压的各项参数值和平均身高、体质量、体质量指数以及生化指标检测结果与全国儿童正常值相比较。结果:49名受试儿童均进入结果分析。①49名新疆哈萨克族9～10岁儿童24h动态血压平均值114/69mmHg(1mmHg=0.133kPa);白天血压平均值:125/78mmHg;夜间血压平均值:98/56mmHg。动态血压中最初2h的血压值为127/83mmHg,显著高于同等年龄的血压值(P<0.01)。②该地区儿童平均身高、体质量与全国同等地区、同等年龄、同性别的儿童相比均存在显著性差异(P<0.01)。③与全国儿童正常参考值相比,49名哈萨克族儿童血糖、三酰甘油、血肌酐、尿钠在正常范围内,血钠、血钾、总胆固醇、白蛋白、尿钾水平在正常值的下限,高密度脂蛋白、低密度脂蛋白与尿肌酐水平在正常参考值的上限。结论:新疆哈萨克族9～10岁儿童24h动态血压中最初2h的血压值较同等年龄的儿童高,部分血生化指标与全国儿童正常参考值有差异。
OBJECTIVE: To understand the ambulatory circadian rhythm of ambulatory blood pressure in Kazak nationalities aged 9 ~ 10 years old in Xinjiang and determine its biochemical parameters and compare with the national parameters of children. Methods: A total of 49 healthy children aged 9-10 years old in Balikun area of Xinjiang were selected, including 27 males and 22 females. The average age was (9.7 ± 0.5) years, height (139.67 ± 7.51) cm, body weight (30.91 ± 6.15) kg, Quality index (15.73 ± 2.00) kg / m2. Ambulatory blood pressure was monitored by using a non-invasive portable ambulatory blood pressure monitor. Subjects lived for 48 hours. Their diet was self-care and their habits were still the same. Urine volume was correctly collected for 24 hours, and medical history and physical examination were asked. The fasting blood serum was isolated and stored at -40 ℃ under low temperature to be measured. The parameters and mean height, body mass, body mass index and biochemical indexes of ambulatory blood pressure in 49 subjects were compared with those of normal children in China. Results: All the 49 tested children entered the result analysis. ①49 Xinjiang Kazak children 9 to 10-year-old average 24h ambulatory blood pressure 114 / 69mmHg (1mmHg = 0.133kPa); mean blood pressure during the day: 125/78 mmHg; night mean blood pressure: 98/56 mmHg. Ambulatory blood pressure in the first 2h of blood pressure was 127 / 83mmHg, significantly higher than the same age blood pressure (P <0.01). ② The average height and weight of children in this area are significantly different from those of the same area, same age and same sex in the whole country (P <0.01). ③Compared with the normal reference value of children in the country, blood sugar, triglyceride, serum creatinine and urinary sodium in 49 Kazakh children were in the normal range. Serum sodium, potassium, total cholesterol, albumin, Lower limit, high density lipoprotein, low density lipoprotein, and urinary creatinine levels were upper limits of normal reference values. CONCLUSIONS: The blood pressure of 24h ambulatory blood pressure of Kazak ethnic children from 9 to 10 years old in Xinjiang is higher than that of the same age children, and some blood biochemical indicators are different from the normal reference values of children in the country.