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目的了解自贡市8月龄内婴幼儿受母亲抗体水平的影响,为制订预防8月龄内儿童感染麻疹的干预措施提供科学依据。方法采用随机抽样方法在自贡市妇幼保健机构内随机抽取187名0~8月龄内婴幼儿及其母亲,对母亲进行问卷调查,同时采集母婴血标本进行血清抗体检测。结果母亲抗体阳性率为69.5%,达到保护性水平占21.4%。母婴抗体水平具有正相关关系,婴儿抗体随母亲抗体水平上升而上升。结论提高母亲抗体水平有利于提高婴幼儿抗体水平。无论是自然免疫和接种过疫苗的育龄期妇女都应进行麻疹疫苗的强化。
Objective To understand the effects of maternal antibodies in infants and young children aged 8 months in Zigong City to provide scientific evidence for the prevention of measles infection in children aged 8 months. Methods A total of 187 infants aged 0 ~ 8 months and their mothers were randomly selected from MCH institutions in Zigong city. Their mothers were surveyed by questionnaire, and serum samples of maternal and infant were collected for serum antibody testing. Results The positive rate of maternal antibody was 69.5%, reaching a protective level of 21.4%. There is a positive correlation between maternal and infant antibody levels and infant antibodies rise with increasing maternal antibody levels. Conclusion Increasing the level of maternal antibodies is helpful to improve antibody levels in infants and young children. Women of childbearing age, both innate and vaccinated, should be fortified with measles vaccine.