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长效避孕埋植剂的现状上海医科大学妇产科医院（２０００１１）杜明昆本世纪６０年代人们发现硅橡胶能用于长期释放亲脂性药物，１９６６年Ｓｅｇａｌ与Ｃｒｏｘａｔｏ提出了以硅橡胶为载体，在其中填充甾体避孕药，埋植于皮下作为避孕药物的缓释系统。药物以恒定速率缓慢...
Long-acting contraceptive implants status Shanghai Medical University Obstetrics and Gynecology Hospital (200011) Du Mingkun 1960s people found that silicone rubber can be used for the long-term release of lipophilic drugs, Segal and Croxato in 1966 proposed a silicone rubber as a carrier in Which filled with steroidal contraceptives, implanted in the subcutaneous as a contraceptive drug delivery system. Drugs are slow at a constant rate ...