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利福喷丁为利福类药物的衍生物,临床用于治疗耐药性结核病。近年来国内有文献报道,本品可致血小板减少,现概述如下。杨文等报道,患女,64岁。因肺结核给予利福喷丁治疗,服药2d后出现皮肤瘀斑,牙龈出血,查血小板55×109/L,停药后给予对症治疗,1 wk后血小板恢复正常,症状消失。半年后患者自我感觉治疗欠佳,擅自加服本品0.45 g,仅服用1次,即出现恶
Rifampicin is a derivative of the Rifampicin, which is clinically used to treat drug-resistant TB. In recent years, there are domestic literature reports, this product can cause thrombocytopenia, are summarized as follows. Yang Wen and other reports, suffering from women, 64 years old. Pulmonary tuberculosis given rifapentine treatment, 2d after taking the skin ecchymosis, bleeding gums, check platelets 55 × 109 / L, given symptomatic treatment after withdrawal, 1 wk platelets returned to normal, the symptoms disappear. Six months after the patient feel inferior treatment, without adding this product 0.45 g, taking only 1, that is, evil