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目的:对照评价西宁地区行冠状动脉介入治疗的不同性别患者临床特点及疗效。方法:选择我院心内科2007年1月—2009年10月择期行冠状动脉介入治疗的男性患者420例作为男性组;女性患者120例作为对照组(女性组),两组均在术后(6～12)个月行冠状动脉造影随访,所有患者均临床随访1年。结果:入选420例男性患者660处病变,120例女性患者166处病变,两组皆完成随访。男性组血脂异常、陈旧性心肌梗死及吸烟史比例均高于女性组(P<0.01)。左主干、回旋支、右冠状动脉、分叉病变比例男性组高于女性组(P<0.05)。1年随访两组血栓发生率及再狭窄率差异无统计学意义,冠状动脉造影复查率女性组显著低于男性组。结论:在西宁地区左主干、回旋支、右冠状动脉和分叉病变患者男性高于女性,男性患者冠心病危险因素较多,冠状动脉病变较严重,这与该地区特殊自然环境及生活起居、饮食习惯有关,因此该地区人群中,冠心病发病危险因素较平原地区有一定特殊性,但不同性别患者冠状动脉介入治疗后疗效相似。
OBJECTIVE: To evaluate the clinical features and efficacy of different gender patients undergoing coronary intervention in Xining. Methods: A total of 420 male patients undergoing coronary intervention from January 2007 to October 2009 were selected as the male group and 120 female patients as the control group (female group) 6 ~ 12) months follow-up coronary angiography, all patients were followed up for 1 year. RESULTS: A total of 660 lesions in 420 men and 120 lesions in 166 women were included in the study. Both groups were followed up. Male patients with dyslipidemia, old myocardial infarction and smoking history were higher than the female group (P <0.01). The ratio of left main trunk, circumflex branch, right coronary artery and bifurcation in male group was higher than that in female group (P <0.05). There was no significant difference in the rate of thrombosis and restenosis between the two groups at 1 year follow-up. The rates of coronary angiography in the women were significantly lower than those in the men. Conclusion: There are more risk factors for coronary heart disease and more severe coronary artery disease in males than in females in left main trunk, circumflex artery, right coronary artery and bifurcation lesions in Xining. This is in line with the special natural environment and daily life in the area, Eating habits, so the population of the region, the risk factors for coronary heart disease than the plains have some particularities, but different gender patients after coronary intervention similar efficacy.