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目的 探讨性腺影像学诊断和血清雌二醇 (E2 )水平测定在鉴别真性性早熟与单纯性乳房发育中的临床意义。方法 对 3 0例性早熟女童进行了盆腔B超检查 ,测量子宫、卵巢体积 ,并与血清E2 水平进行直线相关分析。结果 单纯性乳房早发育女童子宫、卵巢体积和血清E2 水平随年龄增长而逐渐增加 ,真性性早熟女童与同龄的单纯性乳房早发育 (≥ 6岁组 )儿童比较 ,卵巢体积显著增大且血清E2 水平显著增高。性早熟女童子宫、卵巢体积分别与血清E2 水平呈显著正相关 (P分别 <0 0 1,0 0 5 )。结论 盆腔B超检查和血清E2 水平测定对性早熟的诊断具有一定的鉴别意义。
Objective To investigate the clinical significance of gonadal imaging diagnosis and determination of serum estradiol (E2) levels in differentiating true precocious puberty and simple breast development. Methods 30 cases of precocious girls were examined by pelvic ultrasound, the uterus and ovary volume were measured, and the serum E2 level was linearly correlated. Results The uterus, the ovarian volume and the serum E2 level of the early-developing girls with simple breast increased gradually with the increase of age. Compared with the children of the same-age simple breasts with early age (≥ 6 years old), the volume of the ovary increased significantly, E2 levels were significantly higher. The precocious puberty uterus and ovary volume were positively correlated with serum E2 level (P <0 0 1 05 0 respectively). Conclusion pelvic B-ultrasound and serum E2 levels in the diagnosis of precocious puberty has a certain significance.