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目的 :通过对血清中 6种型别肝炎病毒标志物的检测 ,了解新疆地区各型肝炎流行及分布情况 ,为肝炎防治提供科学依据。方法 :采用放射免疫分析法检测 385份住院病人血清中甲、乙、丙、丁、戊、庚 6种型别肝炎病毒感染标志物抗 -HAV ,HBsAg ,抗 -HBS ,HBeAg ,抗 -HBe ,抗 -HBC ,抗 -HCV ,抗 -HDV ,抗 -HEV和抗 -HGV。并统计各标志物在血清中的分布情况。结果 :有 13种表现 ,以单纯甲型和乙型肝炎病毒感染率最高 ;重叠感染为 18.7% ,主要是甲乙型和乙丙型肝炎病毒重叠感染 ;单纯庚型肝炎病毒感染也占一定比例 ;HBsAg无症状携带者占 2 2 .1%。结论 :应加强全社会卫生宣传教育 ,控制传染源 ,严格对献血员的筛选和无症状HBsAg携带者的管理 ,切断医源性传播和垂直传播 ,减少肝炎发病率 ,对重叠感染者应积极防治 ,动态观察及随防 ,促进肝炎患者尽快康复。
OBJECTIVE: To understand the prevalence and distribution of hepatitis in Xinjiang by detecting six kinds of hepatitis B virus markers in serum and provide a scientific basis for prevention and treatment of hepatitis. Methods: Radioimmunoassay was used to detect anti-HAV, HBsAg, anti-HBS, HBeAg, anti-HBe, anti-HBe and anti-HBe in 6 kinds of hepatitis C virus of 385 inpatients, Anti-HBC, anti-HCV, anti-HDV, anti-HEV and anti-HGV. And statistics of the distribution of the markers in the serum. Results: There were 13 kinds of manifestations, with the highest infection rate of pure type A and type B viruses. The overlap infection rate was 18.7%, mainly due to the overlap infection of hepatitis A and B and hepatitis C. The infection of pure type G virus also accounted for a certain proportion. HBsAg asymptomatic carriers accounted for 21.2%. Conclusion: Public health education should be strengthened to control the source of infection, strict screening of blood donors and management of asymptomatic HBsAg carriers, cut off iatrogenic transmission and vertical transmission, reduce the incidence of hepatitis, and should be actively controlled against overlapping infections , Dynamic observation and with prevention, promote hepatitis patients recover as soon as possible.