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为探讨乙肝患者血清多项蛋白的变化规律及临床意义,检测了118例各型乙肝血清载体蛋白—前白蛋白(PA)、白蛋白(aIb)以及急性期反应蛋白—a_1抗胰蛋白酶(a_1AT)、C反应蛋白(CRP)。结果显示,49.15％患者血清PA降低且与a1b的降低呈一致性,65.51％患者血清aIb正常而PA降低,因此在反应肝损害中,PA比aIb更敏感,同时PA的降低与GPT升高明显一致(P<0.01)。与HBV复制标志及传染性无关(P>0.01)。a_1AT及CRP除急性乙肝及慢活肝时升高外,其他各型乙肝均无明显变化。
In order to explore the change rules and clinical significance of serum multiple proteins in patients with hepatitis B, 118 serum samples of hepatitis B (PA), albumin (aIb) and acute phase reaction protein-a1 antitrypsin (a_1AT ), C-reactive protein (CRP). The results showed that 49.15% of patients with serum PA decreased and consistent with the reduction of a1b, 65.51% of patients with normal serum aIb and PA decreased, so in response to liver damage, PA is more sensitive than aIb, while PA decreased and GPT increased significantly Consistent (P <0.01). No correlation with HBV replication markers and infectious (P> 0.01). a_1AT and CRP in addition to acute hepatitis B and chronic liver increased, the other types of hepatitis B had no significant change.