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①目的探讨人巨细胞病毒（ＨＣＭＶ）特异性转移因子（ＳＴＦ）对活动性巨细胞病毒感染孕妇的治疗作用。②方法以孕妇血清ＨＣＭＶ特异性ＩｇＭ阳性做为ＨＣＭＶ活动性感染的指标，应用普通转移因子（ＴＦ）、高效价免疫球蛋白（ＨＩＧ）及ＳＴＦ分别对５７例、１８例及４６例感染孕妇进行治疗，以血清ＨＣＭＶ－ＩｇＭ转阴作为有效的指标。③结果ＴＦ组的ＨＣＭＶ－ＩｇＭ转阴率为２８．１％（１６／５７）；ＨＩＧ组的转阴率为５５．５％（１０／１８）；ＳＴＦ组的转阴率为５６．５％（２６／４６）。ＳＴＦ的治疗作用优于ＴＦ（χ２＝９．７８０，Ｐ＜０．０１）；而ＳＴＦ与ＨＩＧ对感染孕妇的治疗作用无显著性差异（χ２＝０．０１，Ｐ＞０．０５）。④结论ＳＴＦ对活动性ＨＣＭＶ感染孕妇具有较好的治疗作用。
Objective To investigate the therapeutic effect of human cytomegalovirus (HCMV) -specific transfer factor (STF) on pregnant women with active cytomegalovirus infection. Methods Serum HCMV-specific IgM was used as an indicator of active HCMV infection in 57 pregnant women, 18 pregnant women and 46 pregnant women with high titer immunoglobulin (HGF) and STF Treatment, serum HCMV-IgM negative as a valid indicator. Results The negative rate of HCMV-IgM in TF group was 28.1% (16/57), that in HIG group was 55.5% (10/18), and that in STF group was 56.5% (26/46). The therapeutic effect of STF was better than that of TF (χ2 = 9.780, P <0.01). There was no significant difference between STF and HIG in the treatment of infected pregnant women (χ2 = 0.01, P> 0.05). ④ Conclusion STF active HCMV infection pregnant women have a better therapeutic effect.