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目的分析我院药品不良反应(ADR)发生的特点及其规律,确保临床用药的合理、安全。方法采用回顾性方法,对我院2007～2008年报的100份ADR报告,按患者年龄、性别、给药途径、引起ADR的药品种类、涉及器官或系统以及临床表现等进行统计、分析。结果静脉给药较其他给药途径更易发生ADR(占68.0%);抗感染药物引发ADR的比例最高(占51.0%),其次为神经系统与心血管系统药物。结论加强ADR监控意识,并完善相关报告分析制度,以确保临床用药的安全、有效。
Objective To analyze the characteristics and laws of adverse drug reaction (ADR) in our hospital so as to ensure the rational and safe clinical medication. Methods A retrospective analysis of 100 ADR cases reported in our hospital from 2007 to 2008 was conducted based on patient age, sex, route of administration, type of drug causing ADR, organ or system involved, and clinical manifestations. Results Intravenous administration was more prone to ADR (68.0%) than other routes of administration. Anti-infectives had the highest proportion of ADRs (51.0%), followed by neurological and cardiovascular drugs. Conclusion The monitoring awareness of ADR should be strengthened and the system of reporting analysis should be improved to ensure the safety and effectiveness of clinical medication.