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目的:探讨血液灌流串联透析在有机磷中毒患者治疗中的临床效果。方法:选取本院2013年2月至2015年2月收治的有机磷中毒患者74例,按入院先后顺序分为对照组与观察组。对照组在常规治疗基础上采用血液透析治疗,观察组在常规治疗基础上采用血液灌流串联透析治疗,对比两组患者临床治疗效果。结果:观察组患者临床治疗有效率91.89%,高于对照组患者的81.08%,两组比较,差异具有统计学意义(P<0.05);观察组患者清醒时间、胆碱酯酶活性恢复时间、住院时间等指标短于对照组,观察组患者阿托品用量(208.46±10.52)mg,少于对照组的(613.14±23.45)mg,组间比较,差异具有统计学意义(P<0.05)。结论:血液灌流串联透析治疗在有机磷患者中毒中的应用效果显著。
Objective: To investigate the clinical effect of hemoperfusion serial dialysis in the treatment of patients with organophosphate poisoning. Methods: Totally 74 patients with organophosphate poisoning admitted from February 2013 to February 2015 in our hospital were divided into control group and observation group according to the order of admission. The control group was treated with hemodialysis on the basis of routine treatment. The observation group was treated with hemodialysis series dialysis on the basis of routine treatment, and the clinical treatment effect was compared between the two groups. Results: The effective rate of clinical treatment in observation group was 91.89%, which was higher than that in control group (81.08%). There was significant difference between the two groups (P <0.05); the awake time, recovery time of cholinesterase activity, The duration of hospital stay was shorter than that of the control group. The amount of atropine in the observation group was (208.46 ± 10.52) mg less than that of the control group (613.14 ± 23.45) mg. The differences between the two groups were statistically significant (P <0.05). Conclusion: The hemodialysis series dialysis treatment is effective in the poisoning of organophosphate patients.