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本文是应用水模型模拟PET-CT实际检查检测同机融合图像的配准误差。首先制备含59.2 MBq[氟18]-氟代脱氧葡萄糖的水模型,静置80 min,采集2D PET图像20 min,然后经形态学处理与阈值法得水的CT与PET图像,把两组图像的质心位置经线性回归方程拟合,求配准误差。并用Alignment软件测量CT与PET成像系统配准误差4次。得出水PET图像质心较CT图像在X轴偏移(0.011×层数+0.63)mm;在Y轴质心偏移(0.022×层数+1.35)mm,PET图像须经平移且X轴须旋转(0.06±0.07)、Y轴旋转(0.01±0.08)才能与CT图像配准。所以检查床的负载与分布不影响本PET/CT仪系统的配准校正,测量坐标轴旋转角度的随机误差易使PET与CT配准产生偏差。
This paper is the application of water model simulation PET-CT actual inspection to detect the same machine fusion image registration error. First, a water model containing 59.2 MB of [Fluoro 18] -fluorodeoxyglucose was prepared and left to stand for 80 min. 2D PET images were collected for 20 min. The CT images and PET images of water were obtained by morphological and threshold methods. Like the location of the center of mass linear regression equation fitting, find the registration error. Alignment software was used to measure the registration error between CT and PET imaging system 4 times. (0.011 × number of layers +0.63) mm in the center of gravity of the PET image; the center of mass at the Y axis (0.022 × number of layers +1.35) mm, PET image to be translated and the X axis to be rotated 0.06 ± 0.07), Y axis rotation (0.01 ± 0.08) can be registered with CT images. Therefore, the load and distribution of the examination bed does not affect the registration and correction of the PET / CT system. Measuring the random error of the rotation angle of the coordinate axis tends to make the registration between the PET and the CT deviate.