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结核性脑膜炎的病原治疗应尽早、有效及长程。对疑似病人应立即行抗结核治疗；以大剂量异烟肼［１．２ｇ／ｄ，儿童２５ｍｇ／（ｋｇ·ｄ）］静脉滴注（静滴）、吡嗪酰胺、乙胺丁醇及链霉素为最佳联合；重症及晚期病人加鞘内注射链霉素及皮质激素；出现肝毒性则减少、停用吡嗪酰胺或改异烟肼为鞘内注射，以及利福平通过脑脊液储存囊行脑室内给药。疗程需２ａ。
The pathogen of tuberculous meningitis should be treated as soon as possible, effective and long-term. The suspected patients should be immediately treated with anti-TB; high-dose isoniazid [1.2g / d, children 25mg / (kg · d)] intravenous infusion (intravenous infusion), pyrazinamide, ethambutol and chain Mycophenolate for the best combination; severe and advanced patients intrathecal injection of streptomycin and corticosteroids; reduce the occurrence of hepatotoxicity, disable the pyrazinamide or isoniazid for intrathecal injection, and rifampin storage through the cerebrospinal fluid Capsule intraventricular administration. Course of treatment required 2a.