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动脉粥样硬化所致的心、脑血管疾病是目前危害人类健康的首要疾病。1999年Ross提出了动脉粥样硬化是一种炎症性疾病的理论,近来这一理论逐渐被人们所认同,许多学者通过实验在动脉粥样硬化斑块中发现了许多活化的免疫细胞,并证实它们参与了动脉粥样硬化的发生和发展;另外,热休克蛋白60、氧化性低密度脂蛋白等还被认为是动脉粥样硬化的相关抗原,越来越多的实验正在深入地探讨动脉粥样硬化的免疫学防治,相关领域的研究正日益受到人们广泛的关注。
Atherosclerosis caused by heart and cerebrovascular disease is currently the leading disease that endangers human health. In 1999, Ross put forward the theory that atherosclerosis is an inflammatory disease. Recently, this theory has been gradually acknowledged. Many scholars have experimentally found many activated immune cells in atherosclerotic plaque and confirmed They are involved in the occurrence and development of atherosclerosis; In addition, heat shock protein 60, oxidized low density lipoprotein, etc. are also considered atherosclerosis-related antigens, more and more experiments are in-depth discussion of atherosclerosis The research on immunology prevention and cure of sclerosis and related fields is attracting more and more attention.