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目的探究硫酸镁联合米索前列醇治疗妊高征产后出血的疗效。方法选取2013年3月—2014年3月长葛市卫校附属医院收治的妊高征患者134例,随机分为对照组和研究组,每组67例。对照组采用米索前列醇治疗,研究组采用硫酸镁联合米索前列醇治疗。比较两组患者治疗后产后出血量(2h内出血量、24h内出血量)、血压控制情况(收缩压、舒张压)及水肿、头痛、右上腹痛、昏迷情况。结果研究组患者治疗后2h内出血量和24h内出血量均少于对照组,收缩压和舒张压均低于对照组,差异有统计学意义(P<0.05)。研究组患者水肿、头痛及右上腹痛及昏迷发生率均低于对照组,差异有统计学意义(P<0.05)。结论硫酸镁联合米索前列醇治疗妊高征产后出血的疗效显著,能有效控制患者产后出血量和血压。
Objective To investigate the curative effect of magnesium sulfate combined with misoprostol in the treatment of hemorrhage after pregnancy induced hypertension. Methods From March 2013 to March 2014, 134 cases of pregnancy induced hypertension (PIH) admitted to the Changge Medical School Affiliated Hospital were randomly divided into control group and study group, with 67 cases in each group. The control group was treated with misoprostol, and the study group was treated with magnesium sulfate combined with misoprostol. The postpartum hemorrhage volume (2h, 24h), blood pressure control (systolic pressure, diastolic pressure) and edema, headache, right upper quadrant pain and coma were compared between the two groups. Results In the study group, the amount of hemorrhage within 2 hours and the amount of hemorrhage within 24 hours after treatment were both less than those of the control group. The systolic and diastolic blood pressures were lower in the study group than in the control group (P <0.05). The study group patients with edema, headache and right upper quadrant pain and coma incidence were lower than the control group, the difference was statistically significant (P <0.05). Conclusion Magnesium sulfate combined with misoprostol in the treatment of postpartum pregnancy induced hypertension significant effect of bleeding, can effectively control the amount of postpartum hemorrhage and blood pressure.