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肺癌发病率高、死亡率高。而对于肺癌患者来说,其自身免疫系统在与肿瘤对抗过程中起着至关重要的作用,其中免疫细胞尤其是浸润于癌组织中的几种免疫细胞:肿瘤浸润淋巴细胞(TILS)、肿瘤相关巨噬细胞(TAMS)、肿瘤浸润树突状细胞(TIDC)、肿瘤浸润NK细胞(TINK)扮演着重要角色。大量研究表明肿瘤浸润的各种免疫细胞与肺癌患者预后相关,并在抗肿瘤、肿瘤的免疫监视或免疫逃逸、促进肿瘤的发生发展和演进等各方面发挥着重要的作用。
High incidence of lung cancer, high mortality. For lung cancer patients, the autoimmune system plays an important role in the process of tumor confrontation. Immune cells, especially several immune cells infiltrating into cancer tissues, are tumor infiltrating lymphocytes (TILS), tumor Related macrophages (TAMS), tumor infiltrating dendritic cells (TIDC), tumor infiltrating NK cells (TINK) play an important role. Numerous studies have shown that various immune cells infiltrated by the tumor are associated with the prognosis of patients with lung cancer and play an important role in anti-tumor, immune surveillance of immune cells, immune escape, promotion of the development and progression of tumors.