1,3-Dipolar Cycloaddition of Substituted Benzonitrile Oxide to 5-(R)-(l-Menthyloxy)-2(5H)-furanone

• 出 处: Chinese Chemical Letters
• 发表日期: 2002年07期
• 关键词: substituted chiral lactone stirring afford benzene reactivity reagent completed

Several isoxazoline compounds were obtained by the 1,3-dipolar cycloaddition of benzonitrile oxide to 5-(R)-(l-menthyloxy)-2(5H)-furanone. The reaction condition was investigated preliminarily, the structures of these compounds have been established via the analysis of NMR data(involved NOEID or HMBC) and the reaction seems occurred regioselectively.

Several isoxazoline compounds were obtained by the 1,3-dipolar cycloaddition of benzonitrile oxide to 5- (R) - (l-menthyloxy) -2 (5H) -furanone. The reaction condition was investigated preliminarily, the structures of these compounds have been established via the analysis of NMR data (involving NOEID or HMBC) and the reaction like occurred regioselectively.