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目的:观察纳洛酮对心肺脑复苏的临床疗效。方法:选取中山市博爱医院于2009年1月至2012年12月收治的60例心脏骤停患者,按随机数表法分为对照组和观察组,每组30例。所有患者在第一时间内均行胸外按压并经口气管插管呼吸机辅助通气,建立至少2条以上的静脉通道给予肾上腺素静脉推注和补液升压,严密心电监护。对照组患者采取上述抢救措施,观察组在对照组的基础上加以纳洛酮药物治疗。抢救结束后对比分析两组患者的复苏成功率和效果。结果:观察组患者的复苏成功率33.33%,对照组患者的复苏成功率26.67%,差异具有统计学意义(P<0.05)。结论:对心脏骤停患者实行心肺脑复苏时加用纳洛酮能提高复苏成功率。
Objective: To observe the clinical effect of naloxone on cardiopulmonary resuscitation. Methods: Sixty patients with cardiac arrest who were treated in Pok Oi Hospital of Zhongshan City from January 2009 to December 2012 were divided into control group and observation group according to random number table method, with 30 cases in each group. All patients underwent chest compressions and ventilator-assisted ventilation with orotracheal intubation for the first time. At least 2 venous passages were established to give intravenous boluses of adrenaline and fluid replacement, and strict ECG monitoring. The control group of patients to take the above-mentioned rescue measures, the observation group on the basis of the control group to naloxone drug treatment. After the rescue, the success rate and effect of resuscitation in both groups were compared. Results: The success rate of recovery was 33.33% in the observation group and 26.67% in the control group, the difference was statistically significant (P <0.05). Conclusion: Adding naloxone to cardiopulmonary resuscitation in patients with cardiac arrest can improve the success rate of resuscitation.