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心痛定(Nifedipine)用来治疗原发性肺动脉高压症(PPH),特别是长期应用的效果的研究不多。本文作者对4例平均年龄40岁,病程为3个月~47个月(平均21个月)的女性PPH患者,在进行心痛定的急性效果研究的同时又对其表现全肺血管阻力(TPR)显著降低的2例病人,令其口服至2个月后,再次研究其效果;同时还对其中3例进行了亚硝酸制剂消心痛的急性效果研究。短期应用效果,在行心导管检查时,分别测定舌下含服心痛定10mg之前与后10分。20分、30分、40分、60分钟之心率、主动脉压、肺动脉压、心搏出量、动脉血氧分压、
Nifedipine is used to treat primary pulmonary hypertension (PPH), especially in the long term. The authors of this study evaluated 4 acute PPH patients with a mean age of 40 years and a duration of 3 months to 47 months (mean 21 months) in their study of the acute effects of nifedipine, as well as their overall pulmonary vascular resistance (TPR ) Were significantly reduced in 2 patients, making it orally to 2 months later, to study its effect again; also in 3 cases of nitrite-induced anti-heart pain in patients with acute effect study. Short-term effect, in the line of catheter examination, respectively, determination of sublingual convulsions 10mg before and after 10 points. 20 minutes, 30 minutes, 40 minutes, 60 minutes heart rate, aortic pressure, pulmonary artery pressure, stroke volume, arterial partial pressure of oxygen,