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急慢性乙开支病毒性肝炎的肝外表现早有记载,其在急性肝炎常为一过性,而在慢性肝炎则与持续病毒感染发生率和死亡率密切相关,已引起了广大医务工作者的关注.其发病主要为免疫机制所介导,免疫复合物的沉积可能是主要的致病方式,但其他机制也不容忽视,如病毒抗原引起局部免疫复合物的形成,自身抗体形成与组织抗原发生反应和/或病毒直接损伤肝外组织.现将几种公认的慢性乙肝的肝外表现分述如下.1 结节性多动脉炎与慢性乙肝病毒(HBV)感染有关的肝外表现中,最严重的表现之一是全身性、坏死性血管炎,
Acute and chronic hepatitis B virus extrahepatic manifestations of hepatitis has long been documented, its often transient in acute hepatitis, and in chronic hepatitis and persistent viral infection incidence and mortality are closely related to the medical workers have been caused by the Concerned that its incidence is mainly mediated by immune mechanisms, the deposition of immune complexes may be the main pathogenicity, but other mechanisms can not be ignored, such as the formation of local immune complexes by viral antigens, autoantibodies and tissue antigens The reactions and / or viruses directly damage the extrahepatic tissues.Hepatic manifestations of several well-recognized chronic hepatitis B are now described as follows.1 Of the extrahepatic manifestations of polyarteritis nongitis associated with chronic hepatitis B virus (HBV) infection A serious manifestation of systemic, necrotizing vasculitis,