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一、粘膜免疫应答的性质和起源人类粘膜体液免疫的主要保护因子是分泌型膜表面IgA(SIgA),近年研究表明:每天SIgA 分泌量是30~100mg/kg,超过所有其它免疫球蛋白所结合的量。这与SIgA的功能有关,因为它负责保护约几百平方米与外界接触的粘膜表面,这些部位是病原体进入人体的门户。SIgA 是一个多聚体,由两个或两个以上
First, the nature and origin of mucosal immune response Human mucosal humoral immunity is the main protective factor secretory membrane surface IgA (SIgA), recent studies have shown that: daily SIgA secretion is 30 ~ 100mg / kg, more than all other immunoglobulin binding The amount of. This is related to the function of SIgA because it is responsible for the protection of mucosal surfaces that are in contact with the outside world, which are hundreds of square meters in contact with the outside world and are the gateway to entry of pathogens into the human body. SIgA is a multimer, consisting of two or more