论文部分内容阅读
急性有机磷农药中毒经过抢救治疗,在症状明显缓解后的恢复期,病情突然急剧恶化,重新出现有机磷农药中毒症状而且加重,临床上称为反跳。本文就反跳发生的可能原因、临床判定及防治问题,综合各家报道,做初步探讨。 1 反跳的可能原因 1.1 反跳与农药种类、就诊时间、中毒程度有关 农药毒性大和对胆碱酯酶复能剂疗效不佳的种类如久效磷、对硫磷、氧化乐果等较多发生反跳。就诊时间过迟、中毒严重者,由于磷酰化胆碱酯酶老化,可使乙酰胆碱急剧大量堆积而发生反跳。
Acute organophosphorus pesticide poisoning after salvage treatment, in the recovery of symptoms significantly relieved, the sudden and dramatic deterioration of the situation, re-emergence of organophosphorus pesticide poisoning symptoms and aggravated, clinically known as rebound. In this paper, the possible reasons for the occurrence of rebound, clinical judgment and prevention and treatment issues, comprehensive reports, do a preliminary discussion. 1 rebound possible reasons 1.1 rebound and the type of pesticide, treatment time, degree of toxicity related to pesticide toxicity and poor efficacy of the cholinesterase agent such as monocrotophos, parathion, omethoate and more A rebound occurred. Treatment time is too late, severe poisoning, due to phosphorylation of cholinesterase aging, can make a sharp accumulation of large amounts of acetyl rebound occurred.