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本文报道呋喃嘧啶酮治疗班氏丝虫病48例及对照组海群生治疗20例的结果。实验组每天口服呋喃嘧酮20mg/kg×7d,微丝蚴转阴率治毕为60％,治后6个月为80％,其抗丝虫作用比海群生优。副反应以发热、头晕、头痛及胃肠道反应为主,2例黄疸及4例尿中出现RBC。
This paper reports the results of furosemide treatment of 48 cases of Bancroftian filariasis and control group of sea quack treatment of 20 cases. Furosemide 20mg / kg × 7d was given orally daily in the experimental group. The rate of negative conversion of microfilariae was 60% and 80% after 6 months of treatment. The antifibrotic effect was better than that of sea group. Side effects of fever, dizziness, headache and gastrointestinal reactions, 2 cases of jaundice and 4 cases of urinary RBC.