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目的调查萧山区产前筛查状况,探讨产前筛查的价值。方法对2011~2015年的59 923例产前筛查进行回顾性调查分析。结果 5年产前筛查率为84.39%,高风险发生率为4.98%,高风险孕妇产前诊断阳性率为3.13%。随访妊娠结局,高、低风险组孕妇异常妊娠结局发生率分别为3.77%和1.0%。异常妊娠结局率存在显著差异(χ2=183.37,P=0.0000)。结论二联法产前筛查是降低出生缺陷率的有效措施,在普及二联的同时,应针对“二孩”政策全面放开,优化筛查方案,最大程度地避免先天缺陷儿的出生。
Objective To investigate the status of prenatal screening in Xiaoshan District and explore the value of prenatal screening. Methods A retrospective analysis of 59 923 antenatal screening from 2011 to 2015 was conducted. Results The 5-year prenatal screening rate was 84.39% and the high-risk rate was 4.98%. The prenatal diagnosis rate of high-risk pregnant women was 3.13%. Follow-up pregnancy outcome, high and low risk group pregnant women abnormal pregnancy outcomes were 3.77% and 1.0%. Abnormal pregnancy outcomes were significantly different (χ2 = 183.37, P = 0.0000). Conclusion Prenatal screening is an effective measure to reduce the birth defect rate. In the process of popularizing the combination of two births, the policy of “two children” should be fully liberalized to optimize the screening program to avoid the birth defects Born