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目的调查糖尿病足综合治疗过程中高敏C反应蛋白(hs-CRP)的动态变化。方法动态检测了47例糖尿病足患者的血清hs-CRP,并和非糖尿病足的2型糖尿病患者相比较,结果经独立样本的t检验,和对照组比较,研究组首诊即时、治疗7d、14d的血清hs-CRP水平明显升高(P<0.05);有效治疗28d、3个月以及6个月后,研究组血清hs-CRP和对照组相比较,无统计学差异(P>0.05)。结论血清hs-CRP可以作为评价糖尿病足的炎症水平预后指标。
Objective To investigate the dynamic changes of high-sensitivity C-reactive protein (hs-CRP) during the treatment of diabetic foot. Methods The serum hs-CRP levels in 47 patients with diabetic foot were detected dynamically and compared with those in non-diabetic foot type 2 diabetic patients. The results were compared with the control group by independent sample t-test. The level of hs-CRP in the serum of the study group was significantly higher than that of the control group (P <0.05) after 28 days, 3 months and 6 months of effective treatment. There was no significant difference (P> 0.05) . Conclusion Serum hs-CRP can be used as a prognostic indicator of the level of inflammation in diabetic foot.