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目的:探讨益母草注射液联合缩宫素预防阴道分娩产后出血的疗效。方法:选取2012年12月~2013年10月在该院自然分娩的孕妇559名,随机分为实验组(A组,314名)和对照组(B组,245名),A组胎儿娩出断脐后臀部肌注益母草注射液40 mg+缩宫素10 U,并于产后6 h肌注益母草注射液20 mg;B组胎儿娩出断脐后肌注缩宫素10 U,产后6 h肌注缩宫素10 U。观察两组产时及产后1 h、1~2 h、2~24 h阴道出血量及产前产后血压、心率情况。结果:A组产后1 h出血量为(261.08±123.03)ml,1~2h为(60.43±17.25)ml,2~24 h为(57.3±64.2)ml,产后24 h总出血量(402.13±171.21)ml,产后出血率为1.91%;B组分别为(279.18±138.12)ml,(55.33±23.15)ml,(56.16±17.89)ml,(467.89±201.45)ml和6.12%;两组血压、心率、产后1 h及1~2 h出血量比较,差异无统计学意义(P>0.05);A组产后2~24 h出血量、产后24 h总出血量、产后出血发生率均明显低于B组,两组比较,差异有统计学意义(P<0.05)。结论:益母草注射液联合缩宫素可明显减少产后出血量,降低产后出血发生率、疗效确切、副作用少,值得临床推广。
Objective: To investigate the curative effect of motherwort injection combined with oxytocin in preventing postpartum hemorrhage after vaginal delivery. Methods: A total of 559 pregnant women with spontaneous labor in our hospital from December 2012 to October 2013 were randomly divided into experimental group (group A, 314) and control group (group B, 245) After the umbilical posterior gluteal injection of Motherwort injection 40 mg + oxytocin 10 U, and 6 h postpartum intramuscular injection of Motherwort injection 20 mg; B group intrauterine injection of oxytocin umbilicus 10 U, 6 h postpartum muscle injection Elemental Sup 10 U. The duration of vaginal discharge and postpartum 1 h, 1 ~ 2 h, 2 ~ 24 h vaginal bleeding and prenatal blood pressure and heart rate were observed. Results: The amount of bleeding at 1 h postpartum was (261.08 ± 123.03) ml in group A, (60.43 ± 17.25) ml in 1 ~ 2 h and 57.3 ± 64.2 ml in 2 ~ 24 h ), postpartum hemorrhage rate was 1.91%; B group were (279.18 ± 138.12) ml, (55.33 ± 23.15) ml, (56.16 ± 17.89) ml, (467.89 ± 201.45) ml and 6.12% , Postpartum 1 h and 1 ~ 2 h bleeding volume comparison, the difference was not statistically significant (P> 0.05); A group 2 to 24 h postpartum hemorrhage, 24 h postpartum total blood loss, postpartum hemorrhage were significantly lower than the B Group, the difference between the two groups was statistically significant (P <0.05). Conclusion: Motherwort injection combined with oxytocin can significantly reduce the amount of postpartum hemorrhage, reduce the incidence of postpartum hemorrhage, the exact effect, fewer side effects, worthy of clinical promotion.