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在身体内复杂的免疫细胞网络系统中,树突状细胞是最新近才被认识的。淋巴系造血细胞已被全面了解,具有向T淋巴细胞递呈抗原能力的树突状细胞被称作专职抗原递呈细胞,并在启动免疫反应时起关键作用。已公认存在骨髓树突状细胞(DCI)和淋巴系树突状细胞(DC2),其可在异类抗原出现时诱导机体产生免疫和免疫耐受,因为这些潜在的免疫调节功能,树突状细胞已被用于免疫治疗,尤其用于肿瘤免疫接种方面。抱着完全应用于癌症治疗的目的,作者实验室完成了关于人类树突状细胞的实验研究。简介如下:
In the body’s complex immune cell network system, dendritic cells are the most recent known. Lymphoid hematopoietic cells have been fully understood. Dendritic cells that have the ability to present antigens to T-lymphocytes are referred to as professional antigen-presenting cells and play a key role in initiating immune responses. It has been recognized that bone marrow dendritic cells (DCI) and lymphoid dendritic cells (DC2) are present, which can induce immunity and immune tolerance in the presence of heterologous antigens because of these potential immunoregulatory functions, dendritic cells Has been used for immunotherapy, especially for tumor immunization. With the goal of being fully applied to cancer treatment, the author’s laboratory completed an experimental study of human dendritic cells. The brief introduction is as follows: