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目的探讨活性维生素D治疗继发性甲状旁腺功能亢进的临床疗效。方法选择北京市通州区潞河医院2003年5月~2007年3月慢性肾功能不全继发甲状旁腺功能亢进患者20例,使用活性维生素D治疗,观察6个月,记录血钙、血磷、钙磷乘积和血清全段甲状旁腺素(iPTH)的变化。结果11例患者血钙明显升高,钙磷乘积有所降低,12例患者iPTH水平显著降低。结论活性维生素D治疗继发性甲状旁腺功能亢进效果良好。
Objective To investigate the clinical efficacy of active vitamin D in the treatment of secondary hyperparathyroidism. Methods Twenty cases of chronic renal insufficiency secondary hyperparathyroidism were treated in Luhe Hospital, Tongzhou District, Beijing from May 2003 to March 2007. The patients were treated with active vitamin D for 6 months. Blood calcium, , Calcium and phosphorus products and whole serum parathyroid hormone (iPTH) changes. Results Eleven patients had a significant increase in serum calcium, a decrease in the product of calcium and phosphorus, and a significant decrease in iPTH levels in 12 patients. Conclusion Active vitamin D treatment of secondary hyperparathyroidism with good results.