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作者用15年左右时间,在瑞典乌普沙拉大学附属医院,观察了1600例伴胸膜斑和(或)与石棉相关的胸膜增厚患者,其中40例病变主要累及肺上叶,全是男性,年龄41~78岁,而且全部患者均有石棉接触史.85%患者有吸烟史。从开始接触石棉之日算起,潜伏期为34年。胸膜顶增厚的平均宽度21mm。21例病变见于右侧,15例累及两肺,只有4例单纯累及左肺。12例行胸膜活检和8例肺活检均显示不同程度的石棉沉着及非特异性胸膜炎。除弥漫性胸膜和肺实质纤维化累及肺的其余
In 15 years or so at the Uppsala University Affiliated Hospital in Sweden, the authors observed 1,600 cases of pleural thickening associated with pleural plaque and / or asbestos, 40 of which mainly involved the upper lobe of the lung, all male, Aged 41 to 78 years old, and all patients had asbestos exposure history, 85% of patients had a history of smoking. Starting from the date of exposure to asbestos, the incubation period is 34 years. Pleural thickening of the average width of 21mm. Twenty-one of the lesions were found on the right, 15 involved both lungs, and only 4 involved the left lung alone. Twelve routine pleural biopsies and 8 biopsies showed varying degrees of asbestosis and nonspecific pleuritis. In addition to diffuse pleural and pulmonary parenchymal fibrosis involving the rest of the lungs