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目的观察异丙托溴铵联合沙丁胺醇及布地奈德雾化吸入治疗毛细支气管炎急性发作的疗效。方法 256毛细支气管炎患儿随机分为对照组和治疗组,均采用综合治疗,治疗组在此基础上加用异丙托溴铵联合沙丁胺醇及布地奈德雾化吸入治疗,对照组加用沙丁胺醇及布地奈德雾化吸入治疗,观察两组患儿用药后症状缓解及肺部哮鸣音减少或消失时间,并比较两组疗效。结果治疗后两组患儿临床症状及体征均有不同程度改善;治疗组在咳嗽、喘憋缓解时间,肺部哮鸣音消失时间及住院天数方面短于对照组(P<0.05),总有效率高于对照组(P<0.05)。结论异丙托溴铵联合沙丁胺醇及布地奈德雾化吸入能迅速改善患者症状,缩短疗程,提高疗效。
Objective To observe the efficacy of ipratropium bromide combined with salbutamol and budesonide inhalation in the treatment of acute episode of bronchiolitis. Methods 256 children with bronchiolitis were randomly divided into control group and treatment group. All the patients were treated with combination therapy. The treatment group was treated with ipratropium bromide plus salbutamol and budesonide inhalation. The control group was treated with salbutamol And budesonide inhalation therapy were used to observe the two groups of children after treatment symptoms and pulmonary wheele reduction or disappearance of time, and compared the efficacy of the two groups. Results After treatment, the clinical symptoms and signs of both groups were improved to some extent. The treatment group was shorter than the control group (P <0.05) in cough, wheezing relieving time, disappearance time of lung wheeze and hospitalization days Efficiency is higher than the control group (P <0.05). Conclusion Ipratropium bromide combined with salbutamol and budesonide inhalation can rapidly improve the symptoms, shorten the course of treatment and improve the curative effect.