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背景 在瓜德罗普岛(法国的西印度群岛),HTLV-Ⅰ的流行病学资料缺乏。研究设计和方法 在1989年1月—1996年12月,应用酶免疫法对59,426名供血者进行了HTLV-Ⅰ抗体筛查,对其中所有重复阳性的样品以Western blot法进行确证。在研究期间,对当时的HTLV-Ⅰ血清阳性率趋势进行研究,对供血、人口统计学和生物学特征进行多因素分析。结果 筛查的供血者中195名被证实为血清学阳性,阳性率为0.33％(95％可信限范围:0.28％～0.38％)。在调研中观察到,HTLV-Ⅰ流
Background In Guadeloupe (West Indies, France), there is a paucity of epidemiological data on HTLV-I. Study Design and Methods From January 1989 to December 1996, 59,426 blood donors were screened for HTLV-I antibody by enzyme immunoassay and all of the replicate positive samples were confirmed by Western blot. During the study, the prevalence of HTLV-I seroprevalence was then studied by multivariate analysis of blood supply, demographics and biological characteristics. RESULTS: Of 195 blood donors who were screened, seropositivity was confirmed with a positive rate of 0.33% (95% confidence interval, 0.28% -0.38%). In the study, HTLV-I flow was observed