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许多研究提示ARDS的发病机理与补体活性增高和肺毛细血管内中性粒细胞的聚集有关。临床研究表明采用测定循环血液中血浆补体活性的方法预测并发ARDS的特异性不高。作者通过检测明显ARDS和大手术后病人支气管肺泡灌洗液(BAL)中C3a des Arg和白蛋白来检查是否并发ARDS,结果发现特异性较高。
Many studies suggest that the pathogenesis of ARDS is associated with increased complement activity and the aggregation of neutrophils in the pulmonary capillaries. Clinical studies have shown that using the method of measuring plasma complement activity in circulating blood predicts the specificity of concurrent ARDS is not high. The authors examined the presence or absence of ARDS by examining C3a des Arg and albumin in patients with clear ARDS and postoperative major bronchial alveolar lavage fluid (BAL) and found that the specificity was high.