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第109届美国泌尿外科学会(AUA)年会于2014年5月在美国佛罗里达州奥兰多市举行。在为期5天的会议中,大会共收录前列腺癌(PCa)相关研究进展摘要1 000余篇,内容涵盖PCa的流行病学新数据、早期筛查新理论、新型分子标志物、手术新方法、去势抵抗性PCa诊疗新理念、基础研究新进展等方面。本文对PCa早期筛查新理论与新型分子标志物方面进行归纳综述,包括PCa的易感因素,睾酮与PCa关系的变革性认识,前列腺特异性抗原、新型分子标志物和新影像技术在PCa早期诊断中的新应用。
The 109th Annual Meeting of the American Society of Urological Surgery (AUA) was held in Orlando, Florida, USA, in May 2014. During the 5-day conference, the conference included over 1,000 articles about PCa related research progress, covering new epidemiological data of PCa, new theory of early screening, new molecular markers, new methods of surgery, Castration resistance PCa new concept of treatment, new progress in basic research and so on. This review summarizes the new theories of PCa screening and novel molecular markers, including PCa susceptibility factors, transformative understanding of the relationship between testosterone and PCa, prostate-specific antigen, novel molecular markers and new imaging techniques in the early stage of PCa New application in diagnosis.