【摘 要】
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目的 观察卡维地洛与比索洛尔治疗慢性心力衰竭患者的临床疗效.方法 126例慢性心力衰竭患者,采用计算机随机分组的方法分为卡维地洛组与比索洛尔组,每组63例.卡维地洛组患者
【机 构】
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277200,山东省枣庄市山亭区人民医院277200,枣庄学院;
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目的 观察卡维地洛与比索洛尔治疗慢性心力衰竭患者的临床疗效.方法 126例慢性心力衰竭患者,采用计算机随机分组的方法分为卡维地洛组与比索洛尔组,每组63例.卡维地洛组患者给予卡维地洛片进行治疗,比索洛尔组患者给予比索洛尔片进行治疗.观察比较两组患者治疗前后胰岛素抵抗指数和治疗后血管内径水平.结果 治疗后,卡维地洛组患者的血管内径为(8.72±5.42)mm,比索洛尔组患者的血管内径为(5.38±3.21)mm;卡维地洛组患者的血管内径明显优于比索洛尔组,差异具有统计学意义(P0.05);比索洛尔组患者治疗前后的胰岛素抵抗指数比较,差异无统计学意义(P>0.05);治疗后,卡维地洛组患者的胰岛素抵抗指数显著低于本组治疗前及比索洛尔组治疗后,差异具有统计学意义(P<0.05).结论 卡维地洛能够很好地改善血管内皮舒张功能及胰岛素抵抗.
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