甲状腺素治疗肝硬化所致低T_3T_4,Alb血症的临床评价

• 作 者: 沙新平 王本莲 张云翔 罗固全
• 机 构: 湖南省桃源县人民医院内科!桃源415700,湖南省桃源县人民医院内科!桃源415700,湖南省桃源县人民医院内科!桃源415700,湖南省桃源县人民医院内科!桃源415700
• 出 处: 吉林医学院学报(自然科学版)
• 发表日期: 1998年04期
• 关键词: T_3T_4 Alb 血清白蛋白 血症 临床疗效 综合评价 腹水形成 假小叶 肝细胞变性 失代偿期患者 肝功能改变

目的：综合评价甲状腺素治疗肝硬化所致低T3、T4、Alb血症的临床疗效。方法：对45例肝硬化腹水患者随机分成2组，实验组给予甲状腺素片40mg／d，分别于2、4周测定血清T3、T4、Alb，并对其结果进行统计学分析。结果：肝硬化病人普遍存在血清T3、T4、Alb降低现象，当给予甲状腺素后血清中T3、T4、Alb可于2周后显著提高，并于4周时达稳定状态，病人一般情况明显好转。结论：口服甲状腺素对肝硬化致低T3、T4、Alb血症具有显著的治疗意义。

Objective: To evaluate the clinical effect of thyroxine on the treatment of low T3, T4 and Alb in cirrhosis. Methods: Forty-five patients with cirrhosis and ascites were randomly divided into two groups. The experimental group was given thyroxin tablets 40mg / d. Serum T3, T4 and Alb were measured at 2,4 weeks, and the results were statistically analyzed. Results Serum levels of T3, T4 and Alb were generally decreased in patients with cirrhosis. Serum levels of T3, T4 and Alb in serum were significantly increased after 2 weeks and reached steady state at 4 weeks after the administration of thyroxine. The general condition of the patients was significantly improved. Conclusion: Oral thyroxine has a significant therapeutic effect on the low serum levels of T3, T4 and Alb in cirrhotic patients.