Phytochemical screening and wound healing potential of Cuscuta reflexa

来源 :Journal of Chinese Pharmaceutical Sciences | 被引量 : 0次 | 上传用户:smilezhangnan
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The present study was to investigate pharmacognostical, phytochemical and pharmacological properties of extracts from stem of Cuscuta reflexa Roxb. Standard procedures have been followed to evaluate the pharmacognostical properties and preliminary screening of phytochemicals of Cuscuta reflexa Roxb. Albino Wistar rats(either sex) weighing 150–200 g were taken and made to acclimatize by providing them with the appropriate room conditions in the experimental room. Excision wound model has been selected for analgesic and wound healing activity for evaluating potential of the water-extract and ethanolic extract from the stem of Cuscuta reflexa Roxb. The macroscopic and microscopic studies showed the various characteristic features of stems. Preliminary screening of phytochemicals reveled that alkaloids, glycosides, flavonoids were the major groups of phytochemicals present in the successive extracts. Water and ethanolic extracts from stem of Cuscuta reflexa Roxb at 200 mg/kg and 400 mg/kg were able to alleviate pain and wounds. It is concluded that the stems of Cuscuta reflexa Roxb have a markedly therapeutic potential to heal wound and may provide the pharmacological basis for its folk uses. The present study was to investigate pharmacognostical, phytochemical and pharmacological properties of extracts from stem of Cuscuta reflexa Roxb. Standard procedures have been followed to evaluate the pharmacognostic properties and preliminary screening of phytochemicals of Cuscuta reflexa Roxb. Albino Wistar rats (either sex) weighing 150 -200 g were taken and made to acclimatize by providing them with the appropriate room conditions in the experimental room. Excision wound model has been selected for analgesic and wound healing activity for evaluating potential of the water-extract and ethanolic extract from the stem of Cuscuta Reflexa Roxb. The macroscopic and microscopic studies showed the various characteristic features of stems. Preliminary screening of phytochemicals reveled that alkaloids, glycosides, flavonoids were the major groups of phytochemicals present in the past extracts. Water and ethanolic extracts from stem of Cuscuta reflexa Roxb at 200 mg / kg and 400 mg / k g are able to alleviate pain and wounds. it is concluded that the stems of cuscuta reflexa roxb have a markedly therapeutic potential to heal wound and may provide the pharmacological basis for its folk uses.
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