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目的:探讨输尿管镜碎石术与内科保守疗法用于妊娠期输尿管结石治疗临床疗效及安全性差异。方法:选取2013年1月~2014年12月收治妊娠期输尿管结石患者共150例作为研究对象,依据治疗意愿分为对照组(75例)和观察组(75例),分别采用内科保守疗法和输尿管镜碎石术治疗;比较两组患者临床疗效、肾绞痛再发率及妊娠结局情况等。结果:观察组患者临床疗效显著优于对照组,差异有统计学意义(P<0.05);观察组患者肾绞痛再发率显著低于对照组,差异有统计学意义(P<0.05);观察组患者妊娠结局情况显著优于对照组,差异有统计学意义(P<0.05)。结论:输尿管镜碎石术用于妊娠期输尿管结石治疗可有效提高结石清除效果,降低肾绞痛再发风险,并有助于改善妊娠结局,效果优于内科保守疗法。
Objective: To investigate the clinical efficacy and safety of ureteroscopic lithotripsy and conservative medical therapy for gestational ureteral calculi. Methods: A total of 150 patients with ureteral calculi during pregnancy from January 2013 to December 2014 were selected as the study subjects, which were divided into control group (n = 75) and observation group (n = 75) according to the intention of treatment. Ureteroscopy lithotripsy treatment; clinical efficacy of the two groups were compared, the recurrence rate of renal colic and pregnancy outcome and so on. Results: The clinical efficacy of observation group was significantly better than that of control group (P <0.05). The recurrence rate of renal colic in observation group was significantly lower than that of control group (P <0.05). The observation group patients pregnancy outcome was significantly better than the control group, the difference was statistically significant (P <0.05). Conclusion: Ureteroscopic lithotripsy for the treatment of ureteral calculi during gestation can effectively improve the stone removal, reduce the risk of recurrent renal colic, and help to improve the pregnancy outcome, the effect is better than the medical conservative treatment.