Novel screening test for celiac disease using peptide functionalised gold nanoparticles

• 作 者: Anantdeep Kaur Olga Shimoni Mi
• 机 构: InstituteforBiomedicalMaterialsandDevices,SchoolofLifeSciences
• 出 处: 世界胃肠病学杂志:英文版
• 发表日期: 2018年47期
• 关键词: CELIAC disease SEROLOGICAL POINT-OF-CARE Gold nanoparticles Diagnostic test AUTO
• 基金项目: Supported by the Australian Government Research Training Program Scholarship,No.IH150100028,the Australian Research Council,National Health and Medical Research Council for financial support,No.APP110

AIM To develop a screening test for celiac disease based on the coating of gold nanoparticles with a peptide sequence derived from gliadin,the protein that triggers celiac disease.METHODS 20 nm gold nanoparticles were first coated with NeutrAvidin.A long