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目的:探讨显微手术治疗脑胶质瘤的临床效果及对术后认知功能的影响。方法:选取2016年3月至2019年3月辽宁省人民医院神经外一科收治的80例脑胶质瘤患者，男49例，女31例，年龄(45.12±2.34)岁，年龄范围为23～63岁，采用随机数表法将患者随机分为传统手术组和显微手术组，每组40例。传统手术组给予常规手术治疗，显微手术组给予显微手术治疗，比较两组患者的治疗效果、围术期指标及术后认知功能。结果:显微手术组的有效率[92.5%(37/40)]高于传统手术组[75.0%(30/40)]，差异有统计学意义(n P<0.05)。显微手术组手术时间[(64.98±5.33)min]、术中出血量[(165.41±5.31)ml]、住院时间[(6.84±0.92)d]、术后下床时间[(3.30±2.55)d]均优于传统手术组[(90.25±8.12)min、(285.54±6.22)ml、(11.25±1.18)d、(7.25±2.71)d]，差异有统计学意义(n P<0.05)。显微手术组的简易智力状态检查量表(MMSE)评分[(27.54±2.15)分]和改良长谷川痴呆量表(HDS-R)评分[(25.98±2.17)分]高于传统手术组[(20.12±3.20)分、(20.24±4.33)分]，差异有统计学意义(n P<0.05)。n 结论:显微手术治疗脑胶质瘤的临床效果显著，能够有效地促进改善患者的术后认知功能，且围术期指标表现更好。“,”Objective:To investigate the clinical efficacy of microsurgery for glioma and its effect on postoperative cognitive function.Methods:A retrospective study was performed on 80 cases of patients with glioma who were admitted to the department of Neurosurgery, the People’s Hospital of Liaoning Province from March 2016 to March 2019, there were 49 males and 31 females, aged(45.12±2.34) years old, ranging from 23 to 63 years old.Patients were randomly divided into the traditional surgery group and microsurgery group, with 40 cases in each group.The traditional surgery group of patients were performed conventional surgery, and the microsurgery group of patients were performed microsurgery.The therapeutic effects, perioperative indicators and postoperative cognitive function scores of the two groups were compared.Results:The total effective rate of the microsurgery group[92.5%(37/40)]was higher than that of the traditional surgery group[75.0%(30/40)], and the difference was statistically significant(n P<0.05). The operation time[(64.98±5.33) min ], blood loss during operation[(165.41±5.31) ml ], hospital stay[(6.84±0.92) d ]and postoperative time of getting out of bed[(3.30±2.55) d ]in microsurgery group were better than those in traditional surgery group[(90.25±8.12) min, (285.54±6.22) ml, (11.25±1.18) d, (7.25±2.71) d ], the difference was statistically significant(n P<0.05). mini-mental state examination scores[(27.54±2.15) points]and Hasegama’s dementia scale scores[(25.98±2.17) points]in the microsurgery group were higher than those in the traditional surgery group[(20.12±3.20) points, (20.24±4.33) points], (n P<0.05).n Conclusion:The clinical effect of microsurgery in the treatment of glioma is significant, which can effectively promote and improve the postoperative cognitive function of patients, and the performance of perioperative indicators is better.